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Rey Mysterio is no stranger to the word "underdog", as the 5”6 high-flyer had defied the odds on more than one occasion. He is already a multi-time Cruiserweight and Tag Team Champion and he got his big break by winning the 2006 Royal Rumble, a performance that he dedicated to the late, great Eddie Guerrero. He was the second man to enter it, and lasted for over a hour. Mysterio went on to defeat Randy Orton and Kurt Angle at WrestleMania 22 to claim his first World Heavyweight Championship.
Rey Rey's had an illustrious career, often called the "Biggest Little Man" as he's faced all kinds of adversity against much heavier superstars. He didn't always get the job done but he is reputed for the kind of passion he displays in the ring. Lately, Mysterio's momentum has came to several halts due to pursuing injuries. The now SmackDown! superstar is a big hit with the kids and it's positive big things will be in store for him in the future.
 SmackDown!: Here Comes The Pain
 SmackDown! vs Raw
Mysterio has a golden attire and has an overall of 84. He is a face and his finisher is of course The 619.
 SmackDown! vs RAW 2006™
Hardcore: 6Stamina: 10
 SmackDown! vs RAW 2007
Mysterio’s move-set consists mainly of Luchadore holds, and while they may not be very effective, you will gain more momentum by using them. Be sure to check the weight class of your opponent before the match, because some moves such as the Suplex and the Oklahoma slam will be useless against Heavy and Super-Heavyweights. Your best chance of taking down wrestlers of a higher weight class is by using Mysterio’s high-flying moves, with both his speed and stamina attributes at 10, Rey can climb turnbuckle much quicker than most wrestlers, meaning there’s less chance of your opponent standing up before you can attack.
Rey Mysterio is a cruiserweight and can only lift wrestlers of the same or lower weight class than him. With a strength attribute of 6.5 and durability of 7, you may want to stay clear of the likes of Khali and the Big Show if you're new to the game, however if you're experienced in the SmackDown! Series then it can be a good challenge.
Speed: 10Stamina: 10
 SmackDown! vs RAW 2008™
In this game, Rey Mysterio will sport the fighting styles of high-flyer and showman. Meaning that while you jump around the ring with your daredevil antics, you can also taunt to the crowd for some momentum burst. Your speed and charisma will be most influential to you; you also have great stamina which will help you with those high-demanding moves. Possum Pin has also been the M.O. of Rey Rey, and that will be another good asset to help win matches.
Hardcore: 84Stamina: 91
 SmackDown! vs RAW 2009™
This year, Rey's stats have been considerably lowered, but he still doesn't disappoint and remains an entertaining superstar to use, with his high-flying skills and cruiserweight-like abilities. Rey can use the Evasive Dodge, synonymous with the average cruiserweight, and contains the other perks along with that, Outside Dives and Springboard. Due to the lovable character he holds, he is one of the few in the game to contain the Fan Favorite ability, triggering the ability to make the crowd stand on their feet and roar, aggravating/destabilizing his opponent, whoever it may be.
A second 619 has been put in place for Mysterio this year, one with a Senton and the other with a Body Splash, resulting in a pin.
Speed: 90Stamina: 84
 WWE SmackDown! vs RAW 2010™
 Smackdown vs Raw 2011
Charisma: 80Speed: 85
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